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Dr. Shiming Li's Studies

Research Presentation Natural objects Other research
visiting Professor
Dept. of Food Science
Rutgers University, The State University of New Jersey 		  
   
Research   Citation Journal
1. Jeng-Dian Su, Jui-Hung Yen, Shiming Li, Ching-Yi Weng, Meng-Han Lin, Chi-Tang Ho, Ming-Jiuan Wu.

3′,4′-Didemethylnobiletin induces phase II detoxification gene expression and modulates PI3K/Akt signaling in PC12 cells.


 Free Radical Biology & Medicine, 2012, 52, 126–141
2. Alexander Gosslau, Shiming Li, Chi-Tang Ho, Kuang Yu Chen, Nancy E. Rawson.

The importance of natural product characterization in studies of their anti-inflammatory activity.


   Molecular Nutrition & Food Research, 2011, 55, 74-82.
3. Jui-Hung Yen, Ching-Yi Weng, Shiming Li, Ya-Hsuan Lo, Min-Hsiung Pan, Shih-Hang Fu, Chi-Tang Ho, Ming-Jiuan Wu.

Citrus flavonoid, 5-demethylnobiletin, suppresses scavenger receptor expression in THP-1cells and alters lipid homeostasis in HepG2 liver cells.


   Molecular Nutrition & Food Research, 2011, 55, 733-748.
4. Peiju Qiu, Huashi Guan, Ping Dong, Shiming Li, Chi-Tang Ho, Min-Hsiung Pan, David Julian McClements and Hang Xiao.

The p53-, Bax- and p21-dependent inhibition of colon cancer cell growth by 5-hydroxy polymethoxyflavones.

  Molecular Nutrition & Food Research, 2011, 55, 613-622
5. Peiju Qiu, Huashi Guan, Ping Dong, Shanshan Guo, JinKai Zheng, Shiming Li, Yun Chen, Chi-Tang Ho, Min-Hsiung Pan, David J. McClements, Hang Xiao.

The inhibitory effects of 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone on human colon cancer cells.


  Molecular Nutrition & Food Research, 2011, 55, 1523-1532.
6. Ching-Shu Lai, Mei-Ling Tsai, An-Chin Cheng, Shiming Li, Chih-Yu Lo, Yu Wang, Hand Xiao, Chi-Tang Ho, Ying-Jan Wang, and Min-Hsiung Pan.

Chemoprevention of colonic tumorigenesis by dietary hydroxylated polymethoxyflavones in azoxymethane treated mice.


   Molecular Nutrition & Food Research, 2011, 55, 278-290.
7. Shiming Li, Yu Wang, Zhenyu Wang, Hang Xiao, Chih-Yu Lo, Nancy E. Rawson, Chi-Tang Ho.

Quantitative analysis of hydroxylated polymethoxyflavones by high-performance liquid chromatography.


   Biomedical Chromatography, 2010, 24, 838-845.
8. Shiming Li, Chih-Yu Lo, Zhenyu Wang and Chi-Tang Ho.
Edited by C.-T. Ho, C. J. Mussinan, F. Shahidi, and E. Tratras-Contis

Quantitative analysis of six major polymethoxyflavones and six 5-hydroxylated polymethoxyflavones in citrus peels. In Recent Advances in Food and Flavor Chemistry: Food Flavors and Encapsulation, Health Benefits, Analytical Methods, and Molecular biology of Functional Foods.


   The Royal Society of Chemistry, Cambridge, UK, 2010, pp 331-337.
9. Ping Dong, Peiju Qiua, Yi Zhua, Shiming Li, Chi-Tang Ho, David Julian McClements, Hang Xiao.

Simultaneous determination of four 5-hydroxy polymethoxyflavones by reversed-phase high performance liquid chromatography with electrochemical detection.


   Journal of Chromatography A, 2010, 1217, 642-647.
10. Ya-Hsuan Lo, Min-Hsiung Pan, Shiming Li, Jui-Hung Yen,
Mei-Chun Kou, Chi-Tang Ho, Ming-Jiuan Wu.

Nobiletin metabolite, 3′,4′dihydroxy-5,6,7,8-tetramethoxyflavone, inhibits LDL oxidation and down-regulates scavenger receptor expression and activity in THP-1 cells.

   Biochimica et Biophysica Acta, Molecular and Cell Biology of Lipids, 2010, 1801, 114–126.
11. Peiju Qiu, Ping Dong, Huashi Guan, Shiming Li, Chi-Tang Ho, Min-Hsiung Pan, David J. McClements, Hang Xiao.

Inhibitory effects of 5-hydroxyl polymethoxyflavones on colon cancer cells.


  Molecular Nutrition & Food Research, 2010, 54, S244-S252.
12. Shiming Li, Min-Hsiung Pan, Chih-Yu Lo, Di Tan, Yu Wang, Fereidoon Shahidi, Chi-Tang Ho.

Chemistry and health effects of polymethoxyflavones and hydroxylated polymethoxyflavones.


  Journal of Functional Food, 2009, 1 (1), 2-12.
13. Igor N. Sergeev, Shiming Li, Chi-Tang Ho, Nancy E. Rawson,
Slavik Dushenkov.

Polymethoxyflavones activate Ca2+-dependent apoptotic targets in adipocytes.


  Journal of Agricultural and Food Chemistry, 2009, 57(13), 5771-5776.
14. Hang Xiao, Chung S.Yang, Shiming Li, Huanyu Jin, Chi-Tang Ho, Trusha Patel.

Mono-demethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel inhibit growth of human lung cancer cells by apoptosis.


   Molecular Nutrition & Food Research, 2009, 53, 398-406.
15. Shiming Li, Min-Hsiung Pan, Zhenyu Wang, Ted Lambros, Chi-Tang Ho.

Biological activity, metabolism and separation of polymethoxyflavonoids from citrus peels.


   Tree and Forestry Science and Biotechnology, 2008, 2 (Special Issue 1), 36-51.
16. Shiming Li, Yu Wang, Slavik Dushenkov, Chi-Tang Ho

Bioavailability of polymethoxyflavones.

   Dietary Supplements, ACS Symposium Series, 2008, 987, 233-245. Edited by Ho, C.-T.; Shahidi, F.; Shao, Y.; Simon, J.E.
17. Shiming Li, Di Tan, Slavik Dushenkov, Chi-Tang Ho.

Polymethoxyflavones: metabolite identification and pathway, in Dietary Supplements.


   ACS Symposium Series, 2008, 987, 216-232. Edited by Ho, C.-T.; Shahidi, F.; Shao, Y.; Simon, J.E.
18. Shiming Li, Chi-Tang Ho.

The application of chiral HPLC and supercritical fluid chromatography (SFC) in isolation of polymethoxyflavones and identification of PMF metabolites.


   ACS Symposium Series, 2008, 987, 211-215. Dietary Supplements, Edited by Ho, C.-T.; Shahidi, F.; Shao, Y.; Simon, J.E.
19. Shiming Li, Chih-Yu Lo, Slavik Dushenkov, Chi-Tang Ho.

Polymethoxyflavones: chemistry, biological activity and availability from orange peel.


   ACS Symposium Series, 2008, 987.191-210. Dietary Supplements Edited by Ho, C.-T.; Shahidi, F.; Shao, Y.; Simon, J.E.
20. Zhenyu Wang, Shiming Li, Stephen Ferguson, Robert Goodnow, Chi-Tang Ho.

Validated reversed phase LC method for quantitative analysis of polymethoxyflavones in citrus peel extracts.


  Journal of Separation Science, 2008, 31(1), 30-37.
21. Ching-Shu Lai, Shiming Li, Chee-Yin Chai, Chih-Yu Lo, Slavik
Dushenkov, Chi-Tang Ho, Min-Hsiung Pan, Ying-Jan Wang.

Anti-inflammatory and antitumor promotional effects of a novel urinary metabolite, 3',4'-didemethylnobiletin, derived from nobiletin.


   Carcinogenesis, 2008, 29(12), 2415-2424.
22. Shiming Li, Shenmin Sang, Min-Hsiung Pan, Ching-Shu Lai,
Chih-Yu Lo, Chung S.Yang, Chi-Tang Ho.

Anti-inflammatory property of the urinary metabolites of nobiletin in mouse.


  Bioorganic & Medicinal Chemistry Letter, 2007, 17(18), 5177-5181.
23. Shiming Li, Min-Hsiung Pan, Ching-Shu Lai, Chih-Yu Lo,
Slavik Dushenkov, Chi-Tang Ho.

Isolation and syntheses of polymethoxyflavones and hydroxylated polymethoxyflavones as inhibitors of HL-60 cell lines.


  Bioorganic & Medicinal Chemistry, 2007, 15(10), 3381-3389.
24. Shiming Li, Ted Lambros, Zhenyu Wang, Robert Goodnow,
Chi-Tang Ho.

An efficient and scalable method in isolation of polymethoxyflavones from orange peel extract by supercritical fluid chromatography.


   Journal of Chromatography, B: Analytical Technologies in the Biomedical and Life Sciences 2007, 846(1-2), 291-297.
25. Igor N. Sergeev, Shiming Li, Julie Colby, Chi-Tang Ho, Slavik
Dushenkov.

Apoptosis-inducing activity of polymethoxyflavone fractions of orange peel extract in breast cancer cells.


   Molecular Nutrition & Food Research, 2007, 51, 1478-1484.
26. Chi-Tang Ho, Shiming Li, Min-Hsiung Pan, Chih-Yu Lo, Slavik
Dushenkov.

Hydroxylated polymethoxylavone compositions.


   United States patent, US20070275106, PCT Int. Appl. 2007, WO 2007109071 A2.
27. Min-Hsiung Pan, You-Syuan Lai, Ching-Shu Lai, Ying-Jan
Wang, Shiming Li, Slavik Dushenkov, Chi-Tang Ho.

5-Hydroxy-3,6,7,8,3',4'-hexamethoxyflavone Induces Apoptosis through Reactive Oxygen Species Production, Growth Arrest and DNA Damage-Inducible Gene 153 Expression, and Caspase Activation in Human Leukemia Cells.


   Journal of Agricultural and Food Chemistry, 2007, 55, 5081-5091.
28. Ching-Shu Lai, Shiming Li, Chee-Yin Chai, Chih-Yu Lo,
Chi-Tang Ho, Ying-Jan Wang, Min-Hsiung Pan.

Inhibitory effect of citrus 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice.


  Carcinogenesis2007, 28, 2581-2588.
29. Ai Eguchi, Akira Murakami, Shiming Li, Chi-Tang Ho, Hajime
Ohigashi.

Suppressive effects of demethylated metabolites of nobiletin on phobol ester-induced expression of scavenger receptor genes in THP-1 human monocytes cells.


   BioFactors, 2007, 31(2), 107-116.
30. Shiming Li, Zhenyu Wang, Shenmin Sang, Mou-Tai Huang,
Chi-Tang Ho.

Identification of nobiletin metabolites in mouse urine.


   Molecular Nutrition & Food Research, 2006, 50, 291-299.
31. Zhenyu Wang, Shiming Li, Margret Jonca, Stephen Ferguson,
Robert Goodnow, Ch-Tang Ho.

Comparison of supercritical fluid chromatography and liquid chromatography for the separation of urinary metabolites of nobiletin with chiral and non-chiral supporting.


   Biomedical Chromatography, 2006, 20, 1206-1215.
32. Igor N. Sergeev, Shiming Li, Julie Colby, Chi-Tang Ho, Slavik
Dushenkov.

Polymethoxylated flavones induce Ca2+-mediated apoptosis in breast cancer cells.


   Life Sciences, 2006, 80, 245–253.
33. Shiming Li, Chih-Yu Lo, Chi-Tang Ho.

Hydroxylated polymethoxyflavonoids and methylated polyphenols in sweet orange peel.


   Journal of Agricultural and Food Chemistry, 2006, 54(12), 4176-4185.
34. Shiming Li, Haiqing Yu, Chi-Tang Ho.

Efficient and Large scale separation of nobiletin from sweet orange peel extract.

   Biomedical Chromatography, 2006, 20, 133-138.


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Presentation   Citation Journal
1. Shiming Li, Michiko Suzawa.

Efficient treatment of prostate cancer with phytochemicals from citrus genus.


 Abstracts of Papers, The 5th World Cancer Congress 2012, Beijing, China, May 18-20, 2012, CR4303.
2. Michiko Suzawa, Shiming Li.

In vivo anti-tumor activity of polymethoxyflavones from citrus peels.


   Abstracts of Papers, The 5th World Cancer Congress 2012, Beijing, China, May 18-20, 2012, CP0503.
3. Chih-Yu Lo, Yu-Shan Lin, Shiming Li, Min-Shiung Pan, Chi-Tang Ho.

Determination of polymethoxyflavones and monodemethylated polymethoxyflavones in citrus fruits and their tyrosinase inhibition ability.


  Abstracts of Papers, 241st ACS National Meeting,
Anaheim, CA, United States, March 27-31, AGFD-75.
4. Shiming Li, Michiko Suzawa, Terry Nash, Nancy E. Rawson, Chi-Tang Ho.

Health promoting use and composition analysis of commercial citrus peel products.


   Abstracts of Papers, PacifiChem 2010, Honolulu, Hawaii, United States, Dec. 15-20, 2010.
5. Chi-Tang Ho, Shiming Li, Min-Hsiung Pan.

Polymethoxyflavonoids and hydroxylated polymethoxyflavonoids in citrus peels and their potential health beneficial properties.


   Abstracts of Papers, PacifiChem 2010, Honolulu, Hawaii, United States, Dec. 15-20, 2010.
6. Shiming Li, Michiko Suzawa, Terry Nash, Nancy E. Rawson, Chi-Tang Ho.

De-convolution of medicinal citrus products.


   Abstracts of Papers, 240th ACS National Meeting, Boston, MA, United States, Aug. 22-26, 2010, MEDI-238.
7. Hang Xiao, Peiju Qiu, Ping Dong, Chi-Tang Ho, Shiming Li.

Hydroxylated polymethoxyflavones from orange peel as novel cancer preventive agents.


   Abstracts of Papers, 240th ACS National Meeting, Boston, MA, United States, Aug. 22-26, 2010, AGFD-53.
8. Shiming Li, Chi-Tang Ho.

Understanding the natural process of hydroxylated polymethoxyflavone generation in citrus.


   Abstracts of Papers, 238th ACS National Meeting, Washington, DC, United States, Aug 16 -20, 2009, AGFD-064.
9. Shiming Li, Ted Lambros, Peter Savory, Zhenyu Wang, Chih-Yu Lo, Chi-Tang Ho.

The comparison of efficient separation of polymethoxyflavones and hydroxylated polymethoxyflavones.


   Abstracts of Papers, 236th ACS National Meeting, Philadelphia, PA, United States, Aug 17 -21, 2008, AGFD-252.
10. Shiming Li, Chih-Yu Lo, Min-Hsiung Pan, Slavik Dushenkov, Chi-Tang Ho.

The source and biological activity of hydroxylated polymethoxyflavones.


  Abstracts of Papers, 234th ACS National Meeting, Boston, MA, United States, Aug. 19-23, 2007. AGFD-234.
11. Chi-Tang Ho, Shiming Li, Min-Hsiung Pan, Chih-Yu Lo, Slavik Dushenkov.

Bioactive hydroxylated polymethoxyflavones from citrus processing by-products.


  Abstracts of Papers, 232nd ACS National Meeting, San Francisco, CA, United States, Sept 10-14, 2006. AGFD-058.
12. Shiming Li.

Bioavailability and metabolism study of polymethoxyflavones.


   Abstracts of Papers, 230th ACS National Meeting, Washington, DC, United States, Aug. 28- Sept.1, 2005. AGFD-128
13. Zhenyu Wang, Shiming Li, Margret Jonca, Ted Lambros, Stephen Ferguson, Robert Goodnow, Chi-Tang Ho.

Comparison of chiral supercritical fluid chromatography and liquid chromatography for the separation of urinary metabolites of Nobiletin.


   Abstracts of Papers, 230th ACS National Meeting, Washington, DC, United States, Aug. 28- Sept.1, 2005. ANYL-226.
14. Shiming Li, Chi-Tang Ho.

Polymethoxyflavonoids in sweet orange peel: Isolation and in vivo transformation study.


   Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005. AGFD-028.
15. Shiming Li, Chi-Tang Ho.

Isolation and biological properties of polymethoxyflavonoids in sweet orange (Citrus sinensis) peel.


  Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005. AGFD-085.
16. Shiming Li, Chi-Tang Ho.

Efficient and large quantity isolation of nobiletin from sweet orange peel.


  Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005. AGFD-069.
17. Shiming Li, Chi-Tang Ho.

Nobiletin: In vivo transformation study and metabolite identification.

  Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005, AGFD-105.


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Research of natural objects Citation Journal
1. Shiming Li, Chi-Tang Ho.

Metabolism, bioavailability, and safety features of green tea polyphenols.


   In Green Tea Polyphenols, Edited by MP. Kapoor, LR. Juneja, Okubo and Rao, Taylor & Francis Group, Boca Raton, Florida. 2011, in press.
2. Weiya Yun, Mushtaq Ahmad, Yingsi Chen, Paul Gillespie, Karin Conde-Knape, Sonja Kazmer, Shiming Li, Yimin Qian, Rebecca Taub, Stanley J. Wertheimer, Toni Whittard, David Bolin.

Discovery and optimization of 2-phenyloxazole derivatives as diacylglycerol acyltransferase-1 inhibitors.


   Bioorganic & Medicinal Chemistry Letters, 2011, 21(23), 7205-7209.
3. Yimin Qian, Stanley J.bWertheimer, Mushtaq Ahmad, Adrian W-H Cheung, Fariborz Firooznia, Matthew M. Hamilton, Stuart Hayden, Shiming Li, Nicholas Marcopulos, Lee McDermott, Jenny Tan, Weiya Yun, Liang Guo, Anjula Pamidimukkala, Yingsi Chen, Luo-Sen Huang, Gwendolyn B. Ramsey, Toni Whittard, Karin Conde-Knape, Rebecca Taub, Cristina M. Rondinone, Jefferson Tilley, David Bolin.

Discovery of Orally Active Carboxylic Acid Derivatives of 2-Phenyl-5-trifluoromethyloxazole-4-carboxamide as Potent Diacylglycerol Acyltransferase-1 Inhibitors for the Potential Treatment of Obesity and Diabetes.


  Journal of Medicinal Chemistry, 2011, 54(7), 2433-2446.
4. David R. Bolin, Adrian W.-H. Cheung, Fariborz Firooznia, Matthew Hamilton, Shiming Li, Lee A. McDermott, Yimin Qian, Weiya Yun.

Preparation of oxazoledicarboxamides as inhibitors of diacylglycerol acyltransferase (DGAT) useful in the treatment of obesity, diabetes type II and metabolic syndrome.


   U.S. Pat. Appl. Publ., 2010, US 20100190979 A1 20100729.
5. David R. Bolin, Jianping Cai, Adrian W-H Cheung, Robert A. Goodnow Jr., Matthew M. Hamilton, Shiming Li, Lee A. McDermott, Weiya Yun.

Preparation of oxazolecarboxamides and related compounds as diacylglycerol acyltransferase inhibitors.


  U.S. Pat. Appl. Publ. 2009, US 20090076275 A1 20090319.
6. Hsiu W. Yang, Shiming Li, Bu-Xiang Sun, Ling-Zhi Tang, Bo-Feng Wu, Zhi-Hui Wang, Zhen-Peng Chen.

Process of making theaflavins-enriched tea extract.

  PCT Int. Appl. 2009, WO2009014758A1.
7. Chih-Yu Lo, Shiming Li, Yu Wang, Di Tan, Min-Hsiung Pan, Shenmin Sang, Chi-Tang Ho.

Reactive dicarbonyl compounds and 5-(hydroxymethyl)-2-furfural in carbonated beverages containing high fructose corn syrup.


   Food Chemistry, 2008, 107, 1099–1105.
8. Haiqing Yu, Shiming Li, Mou-Tai Huang, Chi-Tang Ho.

Anti-inflammatory constituents in noni (Morinda citrifolia) fruits.


  ACS Symposium Series, No. 987, American Chemical Society: Washington, DC, 2008, 987, 179-190, Dietary Supplements Edited by Ho, C.-T.; Shahidi, F.; Shao, Y.; Simon, J.E.
9. Min-Hsiung Pan, Hui-Jun Kang; Wei-Jen Chen, Chih-Yu Lo, Shiming Li, Shengmin Sang, Chi-Tang Ho.

Induction of apoptosis by acetylated black tea polyphenol through reactive oxygen species production, cytochrome c release, and caspases activation in human leukemia HL-60 cells.


  ACS Symposium Series, 2008, 993(Functional Food and Health), 345-361
10. David R. Bolin, Adrian W-H Cheung, Matthew M. Hamilton, Firooznia Fariborz, Shiming Li, Lee A. McDermott, Yimin Qian, Weiya Yun.

Oxazoledicarboxamides as inhibitors of diacylglycerol acyltransferase (DGAT) and their preparation, pharmaceutical compositions and use in the treatment of obesity, diabetes type II and metabolic syndrome.


  PCT Int. Appl. 2007, WO 2007060140 A2 20070531.
11. Steven J. Berthel, Adrian W-H Cheung, Kyungjin Kim, Shiming Li, Kshitij Thakkar, Weiya Yun.

Preparation of pyrido[2,3-d]pyrimidine-2,4-diamine derivatives as PTP1B inhibitors


  Full Text.PCT Int. Appl. 2007, WO 2007009911 A1 20070125.
12. Chih-Yu Lo, Shiming Li, Di Tan, Min-Hsiung Pan, Shenmin Sang, Chi-Tang Ho.

Trapping Reactions of Reactive Carbonyl Species with Tea Polyphenols in Simulated Physiological Conditions.

  Molecular Nutrition & Food Research, 2006, 50, 1118-1128.
13. Shiming Li, Chi-Tang Ho.

Stability and transformation of bioactive polyphenolic components of herbs in physiological pH


   Herbs:　Challenges in Chemistry and Biology, Edited by M. Wang; S. Sang; L. Sun; C-T. Ho.
ACS Symposium Series, No. 925, American Chemical Society: Washington, DC, 2006 240-253.
14. Hang Chen, Shiming Li, Zhu Zhou, Naisheng Bai, Chi-Tang Ho.

Characterization of chemical components Ixeris denticulata.


  In Herbs: Challenges in Chemistry and Biology, Edited by M. Wang; S. Sang; L. Sun; C-T. Ho. ACS Symposium Series, No. 925, American Chemical Society: Washington, DC, 2006, 195-211.
15. Jin-Woo Jhoo, Chih-Yu Lo, Shiming Li, Shenmin Sang, Catharina Y. W. Ang, Thomas M. Heinze, Chi-Tang Ho.

Stability of black tea polyphenol, theaflavin, and identification of theanaphthoquinone as its major radical reaction product.


   Journal of Agricultural and Food Chemistry. 2005, 53, 6146-6150.
16. Weiya Yun, Shiming Li, Bingbing Wang, Li Chen.

Solid-phase synthesis of diaryl ketones through a three-component Stille coupling reaction.

  Tetrahedron Letters 2001, 42(2), 175-177.


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Other research  Citation Journal
1. Shiming Li.

Tea components, biological activity and product development


   Food Ingredient Conference, Shanghai, China, March 2011.
2. Wenping Tang, Yue Liu, Shiming Li, Henry K. Daun, Mou-Tuan Huang, Chi-Tang Ho.

Hypoglycemic effect of stilbene glycoside from Polygonum multiflorum in KK CgAy/j type 2 diabetic mouse model and its mechanisms.


   Abstracts of Papers, 242nd ACS National Meeting & Exposition, Denver, CO, United States, August 28-September 1, 2011, AGFD-132
3. Shiming Li, Chih-Yu Lo, Nancy E. Rawson, Patricia Lucas-Schnare, Chi-Tang Ho.

Content of nutritional substances in commercial tea beverages


   Abstracts of Papers, 240th ACS National Meeting, Boston, MA, United States, Aug. 22-26, 2010, AGFD-17.
4. Kshitij C.Thakkar, Bruce Banner, Steven Berthel, Jolly Bose, Adrian Cheung, David Fry, Kyungjin Kim, Shiming Li, Garry Mackie, Nicholas Marcopulos, Lucja Orzechowski, Andree Olivier, Joseph A Sergi, Cheryl Spence, Bing-Bing Wang, Weiya Yun, Catherine Zwingelstein.

Aminoquinazolines: Novel and highly selective Protein Tyrosine Phosphatase 1B inhibitors.


  Abstracts of Papers, 239th ACS National Meeting, San Francisco, CA, United States, March 21-25, 2010, MEDI-180 
5. Chih-Yu Lo, Xiu-Yu Chen, Wen Tuan Hsuao, Shiming Li, Min-Hsiung Pan, Chi-Tang Ho.
Trapping of methylglyoxal, a maillard reaction generated bioactive compound, by black currant pigments.


   Abstracts of Papers, 239th ACS National Meeting, San Francisco, CA, United States, March 21-25, 2010, AGFD-83.
6. Chih-Yu Lo, Shiming Li, Yen-Chi Kuo, Min-Haiung Pan, Chi-Tang Ho.

The application of polyphenolic compounds in trapping methylglyoxal and other carbonyl compounds in Maillard reaction.


   Abstracts of Papers, 238th ACS National Meeting, Washington, DC, United States, Aug 16 -20, 2009, AGFD-094. 
7. Weiya Yun, David R. Bolin, Shiming Li, Mushtaq Ahmad, Stanley J. Wertheimer, Karin Conde-Knape, Yingsi Chen, Sonja Kazmer.

Discovery and optimization of oxazole based diacylglycerol acyltransferase 1 inhibitors for the treatment of obesity


   Abstracts of Papers, 237th ACS National Meeting, Salt Lake City, UT, United States, March 22-26, 2009, MEDI-256.
8. Chi-Tang Ho, Pan Min-Hsiung, Shiming Li, Yu Wang.

Anti-inflammatory activity of black tea benzotropolone compounds


   Abstracts of Papers, 236th ACS National Meeting, Philadelphia, PA, United States, August 17-21, 2008, AGFD-255.
9. Chih-Yu, Shiming Li, Yu Wang, Chi-Tang Ho.

Reactive carbonyl species and tea components: Dicarbonyl compounds and 5-(hydroxymethyl)-2-furfural in beverages containing high fructose corn syrup.


   Abstracts of Papers, 234th ACS National Meeting, Boston, MA, United States, August 19-23, 2007, AGFD-232.
10. Shiming Li.

Byproduct isolation and characterization from reductive amination reaction in the synthesis of PEPCK inhibitors.

  Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United States, Mar. 25-29, 2007. ORGN-483.
11. Chih-Yu Lo, Shiming Li, Di Tan, Chia-Pei Liang, Shenmin Sang, Chi-Tang Ho.

Carbonyl stress: generation of reactive carbonyl species and their scavenging by phytopolyphenols.


   Abstracts of Papers, 232nd ACS National Meeting, San Francisco, CA, United States, Sept 10-14, 2006. AGFD-041.
12. Shiming Li, Chi-Tang Ho.

Stability of active polyphenolic ingredients of herbs in physiological pH.


   Abstracts of Papers, 227th ACS National Meeting, Anaheim, CA, United States, March 28-April 1, 2004, AGFD-147.
13. Weiya Yun, Shiming Li, Li Chen

Solid-phase synthesis of diaryl ketones through three-component Stille coupling reaction.

  Abstracts of Papers, 220th ACS National Meeting, Washington, DC, United States, August 20-24, 2000 (2000), ORGN-230.



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